Serial ERG response after dark and light adaptation in comparison to disease severity and fold change of retinal thickness obtained by OCT imaging.

<p>EAU was induced in B10RIII mice by active immunization with IRBP161–180 in CFA. Mice were monitored and followed up at the indicative time points by standard fundoscopy, OCT and ERG. <b>A</b>, EAU clinical scores as determined by clinical examination using standard fundoscopy. <b>B</b>, Fold change of retinal thickness measured by OCT. <b>C</b>, Dark- and light-adapted ERGs during EAU. Data are present as mean ± SEM of 13 mice from two individual experiments. Statistical analyses of retinal thickness are performed using the Mann-Whitney test. *, p<0.05; **, p<0.01.