<p>The putative target gene is shown, with the arrow indicating the transcriptional direction. Arrowheads indicate the genomic location of the viral integrations, with the direction of the arrow indicating the viral transcription direction. Colors indicate the cohort from which the integrations were recovered.</p
Murine leukemia virus (MLV)-derived vectors are widely used for hematopoietic stem cell (HSC) gene t...
<p>(<b>A</b>) Schematic depiction of the MCPyV genome. The binding sites of nested gene specific 5’-...
<p>Sequences for the top 30 enriched transcripts were analysed for HCMV miRNA targets using RNA Hybr...
<p>Genes or intergenic regions were normalized to a common length and then divided into ten interval...
<p>Depicted are integration sites located within the cytogenetic bands 3q28 (A), 4q13.3 (B), 8q24.21...
Integration of retroviral vectors in the human genome follows non random patterns that favor inserti...
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA ...
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA ...
Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cD...
<p>(<b>A</b>) Schematic depiction of the MCPyV genome with polyadenylation and transcriptional initi...
<p>HBV insertions are shown as circles marked with insertion positions. <i>MLL4</i> insertion sites ...
<p>A: Experimental workflow. B: Position of insertions in MCF-7 cells with respect to TSS, showing a...
<p>CISs are indicated by their manually curated target gene. Red edges indicate a co-occurrence rela...
<p>For each of the systems SB, PB, and MMTV, the unselected integrations are divided into genic inte...
<p>CD3/CD28 microbeads-activated PBMCs were transduced at a multiplicity of infection of 20 (Lv) or ...
Murine leukemia virus (MLV)-derived vectors are widely used for hematopoietic stem cell (HSC) gene t...
<p>(<b>A</b>) Schematic depiction of the MCPyV genome. The binding sites of nested gene specific 5’-...
<p>Sequences for the top 30 enriched transcripts were analysed for HCMV miRNA targets using RNA Hybr...
<p>Genes or intergenic regions were normalized to a common length and then divided into ten interval...
<p>Depicted are integration sites located within the cytogenetic bands 3q28 (A), 4q13.3 (B), 8q24.21...
Integration of retroviral vectors in the human genome follows non random patterns that favor inserti...
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA ...
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA ...
Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cD...
<p>(<b>A</b>) Schematic depiction of the MCPyV genome with polyadenylation and transcriptional initi...
<p>HBV insertions are shown as circles marked with insertion positions. <i>MLL4</i> insertion sites ...
<p>A: Experimental workflow. B: Position of insertions in MCF-7 cells with respect to TSS, showing a...
<p>CISs are indicated by their manually curated target gene. Red edges indicate a co-occurrence rela...
<p>For each of the systems SB, PB, and MMTV, the unselected integrations are divided into genic inte...
<p>CD3/CD28 microbeads-activated PBMCs were transduced at a multiplicity of infection of 20 (Lv) or ...
Murine leukemia virus (MLV)-derived vectors are widely used for hematopoietic stem cell (HSC) gene t...
<p>(<b>A</b>) Schematic depiction of the MCPyV genome. The binding sites of nested gene specific 5’-...
<p>Sequences for the top 30 enriched transcripts were analysed for HCMV miRNA targets using RNA Hybr...