Induction of apoptosis by depletion of TTK in triple-negative breast cancer cells.

<p>We transfected MDA-MB-468 (<b>A</b>), HCC70 (<b>B</b>) and MDA-MB-231 (<b>C</b>) and MCF10A (<b>D</b>) cells with the indicated siRNAs. We analyzed the proportion of living and dead cells by FACs following PI and annexin V staining. Histograms with the percentage of apoptotic cells are presented, and are the mean of two to three independent experiments. We show the standard deviation of the mean by error bars and the p values from Student’s <i>t</i> test by asterisks (*p<0.05; **p<0.01).