Cell cycle arrest in G2/M-phase.

<p><b>A</b> Cell cycle analysis of U87MG cells was performed 24 h, 48 h and 72 h after CAP treatment (30 s, 60 s, 120 s and 180 s) by flow cytometry. Treatment was performed only with a thin film of liquid covering the cells. Similar results were observed for the LN229 (MGMT negative) and LN18 (MGMT positive) cells (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064498#pone.0064498.s003" target="_blank">Figure S3</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064498#pone.0064498.s004" target="_blank">Figure S4</a>). <b>B</b> Statistical significances of the observed arrest in the G2/M-phase in U87MG and <b>C</b> in LN18 cells. P-value *** <0.001.