Clonogenic capacity of glioma cells treated with TMZ (B) or CAP (C).

<p>Glioma cells were either TMZ or CAP treated without medium and 24 h later 150 cells/well were seeded on a 6-well plate. Colonies formed after 12 days were stained and counted. P values *** <0.001. <b>A</b> Picture of the LN18 (MGMT positive) cells treated with CAP for 30 s, 60 s and 120 s. Afterwards the formed colonies were stained. <b>B</b> Treatment of glioma cells with TMZ with concentrations of up to 500 µM and colony formation assay was performed afterwards. <b>C</b> CAP treatment followed by the colony formation assay in either MGMT positive or MGMT negative cells.