<p>The top, middle, and bottom graph show copy number, <b>X</b>, elimination coefficient, <b>E</b>, and chromosome number, <b>N</b>, respectively versus number of iterations. Each value represents the average of the population, and each colored line represents a different trial, all with the same parameters. Note that due to the stochastic nature of our simulation we see significant variation between trails using the same parameters, yet the final result is consistent.</p
<p>Multiple executions of the stochastic FluTE model with identical epidemiological configuration le...
<p><b>A</b>) Transitions between the three types considered, wild types (W), resistant types without...
<p>Parameter values are means from the analysis of 10 simulated data sets generated using a model wi...
<p>The figure plots the mean (A) genotype error and (B) clone frequency error as a function of the...
<p>Results for rare variants are shown in red; for the top hit among common variants, results are sh...
<p><b>A.</b> The three genetic arrangements, in simulated diploid chromosomes. Key measurements of e...
<p>Black solid line: relationship between the number of sampled females (X axis) and the diversity o...
<p>Dispersions with gene-wise log geometric mean counts below the median (log mean from 2.17 to 1.63...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
<p>This simulation consisted of 1019 cases of which 119 (12%) were infected by other cases. In total...
<p>a. Example trajectories for a neutral and deleterious allele with current population frequencies ...
(A) Diagram (not to scale) of the demographic model with all the optimized parameters in blue for th...
<p>The three rows reflect three different costs of childbirth. The left graphs reflect the average g...
(a) Joined lines show a single realisation of the population growth obtained via simulation. Dashed ...
<p>Dispersions with gene-wise log geometric mean counts below the median (log mean from −2.17 to 4.4...
<p>Multiple executions of the stochastic FluTE model with identical epidemiological configuration le...
<p><b>A</b>) Transitions between the three types considered, wild types (W), resistant types without...
<p>Parameter values are means from the analysis of 10 simulated data sets generated using a model wi...
<p>The figure plots the mean (A) genotype error and (B) clone frequency error as a function of the...
<p>Results for rare variants are shown in red; for the top hit among common variants, results are sh...
<p><b>A.</b> The three genetic arrangements, in simulated diploid chromosomes. Key measurements of e...
<p>Black solid line: relationship between the number of sampled females (X axis) and the diversity o...
<p>Dispersions with gene-wise log geometric mean counts below the median (log mean from 2.17 to 1.63...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
<p>This simulation consisted of 1019 cases of which 119 (12%) were infected by other cases. In total...
<p>a. Example trajectories for a neutral and deleterious allele with current population frequencies ...
(A) Diagram (not to scale) of the demographic model with all the optimized parameters in blue for th...
<p>The three rows reflect three different costs of childbirth. The left graphs reflect the average g...
(a) Joined lines show a single realisation of the population growth obtained via simulation. Dashed ...
<p>Dispersions with gene-wise log geometric mean counts below the median (log mean from −2.17 to 4.4...
<p>Multiple executions of the stochastic FluTE model with identical epidemiological configuration le...
<p><b>A</b>) Transitions between the three types considered, wild types (W), resistant types without...
<p>Parameter values are means from the analysis of 10 simulated data sets generated using a model wi...