<p>(<b>A, B</b>) Detection of BDNF by western blotting. SH-SY5Y cells were treated with miR-182 or miR-132, the results showed that BDNF expression in the miR-182- or miR-132-treated cultures was much lower than that of negative control miRNA cultures. *<i>P</i><0.05, miR-182- or miR-132-treated cultures <i>vs.</i> control cultures. Relative values for BDNF <i>vs</i>. Actin are indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063648#pone-0063648-g002" target="_blank">Fig.2B</a>.</p
<p>(<b>A</b>) BDNF concentrations in patients and controls. The serum levels of BDNF in the patients...
<p>Representative western blot (<i>A</i>) and cumulative data (<i>B</i>) showing the levels of D1 re...
(A) Inhibitory effects of anti-miR-188 oligo RNA on expression of endogenous miR-188 in C2C12 cells....
<p>(<b>A</b>) Representative gel of the RT-PCR amplification of <i>Nf1</i> mRNA in HEK293 cells tran...
<p>(A) MiR-376b-5p binding site in 3′-untranslated region (3′-UTR) of BDNF gene. (B) Inhibitory effe...
<p>(A) The expression levels of miR-328 in pressurized NRK-52E cells. NRK-52E cells were pressurized...
<p>A, B, C and D : Parental NN10#5 cells and their derivative #17-92a, #17-92b and #17-20 were cultu...
<p>The differentially expressed miRNAs identified by miRNA microarray were confirmed by miRNA Northe...
<p>The effect of BDNF stimulation (for 30 minutes or 3 hours) on microRNA and Arc expression was stu...
<p>To test the efficacy of the sponge we examined whether it altered miR-132 expression in rat PC12 ...
<p>(A) Growth curves of C2C12 myoblasts were determined by MTT assay. Cells were transfected with mi...
<p>A: Fluorescence microscope detection. Scale bars: 150 µm. B: Flow cytometry analysis. n = 3 repli...
<p>(<b>A</b>) Schematic of miRNA plasmids and their expression levels in HEK293 cells. Representativ...
<p>(A) MITF expression in M23 and SP6.5 cells after transfection with miR-182 was dramatically reduc...
<p>A–C, increased BDNF expression correlates strongly with lower miR-204 expression in multiple canc...
<p>(<b>A</b>) BDNF concentrations in patients and controls. The serum levels of BDNF in the patients...
<p>Representative western blot (<i>A</i>) and cumulative data (<i>B</i>) showing the levels of D1 re...
(A) Inhibitory effects of anti-miR-188 oligo RNA on expression of endogenous miR-188 in C2C12 cells....
<p>(<b>A</b>) Representative gel of the RT-PCR amplification of <i>Nf1</i> mRNA in HEK293 cells tran...
<p>(A) MiR-376b-5p binding site in 3′-untranslated region (3′-UTR) of BDNF gene. (B) Inhibitory effe...
<p>(A) The expression levels of miR-328 in pressurized NRK-52E cells. NRK-52E cells were pressurized...
<p>A, B, C and D : Parental NN10#5 cells and their derivative #17-92a, #17-92b and #17-20 were cultu...
<p>The differentially expressed miRNAs identified by miRNA microarray were confirmed by miRNA Northe...
<p>The effect of BDNF stimulation (for 30 minutes or 3 hours) on microRNA and Arc expression was stu...
<p>To test the efficacy of the sponge we examined whether it altered miR-132 expression in rat PC12 ...
<p>(A) Growth curves of C2C12 myoblasts were determined by MTT assay. Cells were transfected with mi...
<p>A: Fluorescence microscope detection. Scale bars: 150 µm. B: Flow cytometry analysis. n = 3 repli...
<p>(<b>A</b>) Schematic of miRNA plasmids and their expression levels in HEK293 cells. Representativ...
<p>(A) MITF expression in M23 and SP6.5 cells after transfection with miR-182 was dramatically reduc...
<p>A–C, increased BDNF expression correlates strongly with lower miR-204 expression in multiple canc...
<p>(<b>A</b>) BDNF concentrations in patients and controls. The serum levels of BDNF in the patients...
<p>Representative western blot (<i>A</i>) and cumulative data (<i>B</i>) showing the levels of D1 re...
(A) Inhibitory effects of anti-miR-188 oligo RNA on expression of endogenous miR-188 in C2C12 cells....