BDNF serum levels and its related miRNAs.

<p>(<b>A</b>) BDNF concentrations in patients and controls. The serum levels of BDNF in the patients with depression (n = 40; 20.05±5.98 ng/ml) were significantly decreased compared with those of the healthy controls (n = 40; 25.22±5.17 ng/ml). (<b>B</b>) The targeting site on BDNF-mRNA-3′UTR by miR-182, which was aligned with the mRNA-3′UTR of human <i>bdnf</i> gene with the nucleotide position. Vertical lines indicate identity.