The relative expression of apoptotic cells in the peri-infarct area (primary motor cortex, M1) (n = 8 for each group).

<p><b>A:</b> Expression of TUNEL positive and Hoechst cells among groups. <b>B:</b> The peri-infarct area for measurement. <b>C:</b> Quantification of the percentage of TUNEL positive cells to Hoechst cells. *, **, <i>P</i><0.05, <i>P</i><0.01 vs. S group; ##, <i>P</i><0.01 vs. C group; ++, <i>P</i><0.01 vs. IGF group. S: Sham control; C: MCAO control; IGF: MCAO with IGF-I treatment; IGF+I: MCAO with AG1024 and IGF-I treatment.