SHAPE-guided secondary structure model for the TBSV RNA genome.

<p>Nucleotides are colour-coded according to their SHAPE reactivities as indicated in the colour key. Nucleotides in grey correspond to regions for which no SHAPE data were available. Nucleotide coordinates and base paired (<i>i.e.</i> stem or helical) regions are numbered in regular and bold type, respectively. The complementary segments known to form functional long-range RNA-RNA interactions are labeled and delineated by black lines. Start and stop codons for viral ORFs are labeled and defined by blue bars, while initiation sites for sg mRNA transcription are denoted by gold arrows. See text for details.