Ontology analysis of genes differentially expressed between EBV blasts and CD40L/IL-4 blasts.

<p>Ontology analysis of genes differentially expressed between EBV and CD40L/IL-4 blasts by paired LIMMA (p<0.01, FC>2) was performed using the DAVID v6.7 bioinformatics resource <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064868#pone.0064868-Huang1" target="_blank">[28]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064868#pone.0064868-Huang2" target="_blank">[29]</a> to identify Panther Biological Processes terms for which there was a significant enrichment of genes. The lists of probe-sets entered into DAVID v6.7 and the complete analyses readouts are given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064868#pone.0064868.s001" target="_blank">Data-File S1</a>. The probe-sets analyzed were those which were: (A) differentially expressed between EBV and CD40L/IL-4 blasts at day 7, (B) the subset of differentially expressed genes that was expressed higher in EBV blasts than in CD40L/IL-4 blasts, and (C) the subset of differentially expressed genes that was expressed lower in EBV blasts than in CD40L/IL-4 blasts.