Heatmap of the miRNA signature in EAC.

<p>The heatmap was generated using the Treeview® software <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0064463#pone.0064463-Page1" target="_blank">[18]</a>. The log10 values of fold expression of the 8 miRNAs (miR-192, miR-200a, miR-194, miR-21, miR-203, miR-205, miR-31, and miR-133b) were used for hierarchical clustering. miR-191 was used as a reference gene. The heatmap indicates the four histological groups of NS, BE (isolated BE or BE adjacent to HGD), HGD, and EAC.