a<p>Negative control: dimethylsulfoxide (DMSO - 100 µL/plate); C+ = Positive control -<sup>b</sup>4 -nitro-o-phenylenediamine (NOPD –10.0 µg/plate – TA98, TA97a);</p>c<p>sodium azide (1.25 µg/plate –TA100);</p>dc<p>mitomycin (0.5 µg/plate – TA102), in the absence of S9 and</p>e<p>2-anthramine (1.25 µg/plate – TA97a, TA98, TA100);</p>f<p>2-aminofluorene (10.0 µg/plate – TA102), in the presence of S9.</p
Abstract: The safety evaluation of new pharmaceutical compounds is paramount, especially in the cont...
In the present study were used reference mutagens which effects mutagenic activity in prokaryotic an...
Induction of chromosome damage in mammalian cells by chemicals generally requires DNA replication an...
a<p>Negative control: dimethylsulfoxide (DMSO - 100 µL/plate); C+ = Positive control -<sup>b</sup>4 ...
ab<p>Differences between groups having the same letter in the same column are not statistically sign...
<p>Mutagenicity measured by the Ames fluctuation assay using TA98 bacteria with and without bioactiv...
The values shown represent the mean number of revertant colonies in the presence and absence of exog...
abcde<p>Differences between groups having the same letter in the same column are not statistically s...
<p><i>S. Typhimurium</i> strains TA98, TA100, TA1535, TA1537 and <i>E. Coli</i> strain WP2 were incu...
<p><sup>1</sup> Negative control: 20 μL dimethylsulfoxide (DMSO).</p><p><sup>2</sup> Positive contro...
<p>Means ± standard deviation (SD) of histidine revertant colonies (obtained from three independent ...
Boots Pharmaceuticals Research Department, Nottingham, UK As a contribution to the third UKEMS colla...
<p>Mutagenic measured by the Ames fluctuation assay using both TA98 and TA100 bacteria strain with a...
Although dialkylnitrosamines are environmentally significant carcinogens, the use of short-term bioa...
Although dialkylnitrosamines are environmentally significant carcinogens, the use of short-term bioa...
Abstract: The safety evaluation of new pharmaceutical compounds is paramount, especially in the cont...
In the present study were used reference mutagens which effects mutagenic activity in prokaryotic an...
Induction of chromosome damage in mammalian cells by chemicals generally requires DNA replication an...
a<p>Negative control: dimethylsulfoxide (DMSO - 100 µL/plate); C+ = Positive control -<sup>b</sup>4 ...
ab<p>Differences between groups having the same letter in the same column are not statistically sign...
<p>Mutagenicity measured by the Ames fluctuation assay using TA98 bacteria with and without bioactiv...
The values shown represent the mean number of revertant colonies in the presence and absence of exog...
abcde<p>Differences between groups having the same letter in the same column are not statistically s...
<p><i>S. Typhimurium</i> strains TA98, TA100, TA1535, TA1537 and <i>E. Coli</i> strain WP2 were incu...
<p><sup>1</sup> Negative control: 20 μL dimethylsulfoxide (DMSO).</p><p><sup>2</sup> Positive contro...
<p>Means ± standard deviation (SD) of histidine revertant colonies (obtained from three independent ...
Boots Pharmaceuticals Research Department, Nottingham, UK As a contribution to the third UKEMS colla...
<p>Mutagenic measured by the Ames fluctuation assay using both TA98 and TA100 bacteria strain with a...
Although dialkylnitrosamines are environmentally significant carcinogens, the use of short-term bioa...
Although dialkylnitrosamines are environmentally significant carcinogens, the use of short-term bioa...
Abstract: The safety evaluation of new pharmaceutical compounds is paramount, especially in the cont...
In the present study were used reference mutagens which effects mutagenic activity in prokaryotic an...
Induction of chromosome damage in mammalian cells by chemicals generally requires DNA replication an...