<p>LVP, left ventricle (LV) pressure; LVESP, LV end-systolic pressure; LVEDP, LV end-diastolic pressure; dP/dt<sub>max</sub>, maximal value of the first derivative of LV pressure; dP/dt<sub>min</sub>, minimal value of the first derivative of LV pressure; ESV, end-systolic volume; EDV, End-diastolic volume; SV, stroke volume; CO, cardiac output; EF, ejection fraction; AE, arterial elastance; SW, stroke work. CON, control; TAC and TAC+IMD mean mice received transverse aortic constriction treatment without and with IMD treatment for 4 weeks, respectively.</p>*<p>P<0.05 and **P<0.01 vs the control;</p>#<p>P<0.05,</p>##<p>P<0.01 vs TAC alone 4 weeks group. TAC, transverse aortic constriction; IMD, intermedin.</p
<p>BW: body weight; EF: ejection fraction; HW: heart weight; LV: left ventricular; LVEDD: Left ventr...
Transverse aortic constriction (TAC) is a frequently used model to investigate pressure overload-ind...
<p>Echocardiography was performed to assess cardiac parameters of n ≥ 10 control (CTL, filled bars) ...
<p>LVSd, left ventricle (LV) end systolic diameter; LVIDd, LV internal dimension in diastole; LVPWd,...
<p>Representative M-mode frames from the mid-papillary region of CON, TAC and TAC+IMD 2 and 4 weeks ...
Cardiac hypertrophy was induced by TAC in male mice. Eight weeks following TAC, left ventricular car...
<p>(A) A<sub>2A</sub>-R mice had preserved cardiac function and showed tolerance to TAC-induced pres...
<p>A) Representative pictures of hearts from sham-operated control and TAC mice treated with vehicle...
(A-F) Left ventricular cardiac functional parameters between male Sirt5 KO mice and WT littermates a...
<p>Quantification of (A) fractional shortening, (B) ejection fraction and (C) left ventricular poste...
<p>Two dimension guided M-mode echocardiography and pathology were performed 4 weeks after the initi...
Left ventricular function assessed by transthoracic echocardiography of db/db mice and age-matched c...
<p>3 d of pressure overload increased the left ventricular systolic pressure (A) and mean arterial b...
<p>Immunofluorescent TUNEL stained heart tissue sections from sham-operated control and TAC mice tre...
<p>BW, body weight; LV, left ventricular; LVPW, LV posterior wall thickness; IVS, interventricular s...
<p>BW: body weight; EF: ejection fraction; HW: heart weight; LV: left ventricular; LVEDD: Left ventr...
Transverse aortic constriction (TAC) is a frequently used model to investigate pressure overload-ind...
<p>Echocardiography was performed to assess cardiac parameters of n ≥ 10 control (CTL, filled bars) ...
<p>LVSd, left ventricle (LV) end systolic diameter; LVIDd, LV internal dimension in diastole; LVPWd,...
<p>Representative M-mode frames from the mid-papillary region of CON, TAC and TAC+IMD 2 and 4 weeks ...
Cardiac hypertrophy was induced by TAC in male mice. Eight weeks following TAC, left ventricular car...
<p>(A) A<sub>2A</sub>-R mice had preserved cardiac function and showed tolerance to TAC-induced pres...
<p>A) Representative pictures of hearts from sham-operated control and TAC mice treated with vehicle...
(A-F) Left ventricular cardiac functional parameters between male Sirt5 KO mice and WT littermates a...
<p>Quantification of (A) fractional shortening, (B) ejection fraction and (C) left ventricular poste...
<p>Two dimension guided M-mode echocardiography and pathology were performed 4 weeks after the initi...
Left ventricular function assessed by transthoracic echocardiography of db/db mice and age-matched c...
<p>3 d of pressure overload increased the left ventricular systolic pressure (A) and mean arterial b...
<p>Immunofluorescent TUNEL stained heart tissue sections from sham-operated control and TAC mice tre...
<p>BW, body weight; LV, left ventricular; LVPW, LV posterior wall thickness; IVS, interventricular s...
<p>BW: body weight; EF: ejection fraction; HW: heart weight; LV: left ventricular; LVEDD: Left ventr...
Transverse aortic constriction (TAC) is a frequently used model to investigate pressure overload-ind...
<p>Echocardiography was performed to assess cardiac parameters of n ≥ 10 control (CTL, filled bars) ...