Directional transport of Imatinib (A) and INNO-406 (B) across BBMEC monolayers.
- Syed Z. Imam (9598)
- William Trickler (583617)
- Shinya Kimura (247648)
- Zbigniew K. Binienda (583618)
- Merle G. Paule (286185)
- William Slikker Jr (583619)
- Senlin Li (391558)
- Robert A. Clark (269615)
- Syed F. Ali (583620)
Publication date
May 2013
DOIAbstract
<p>The directional transport of two drug analogues Imatinib (A) and INNO-406 (B) were determined in BBMEC. The apical-to-basolateral transport (A→B) (open circles) and basolateral-to-apical (B→A)(closed circles). The data are presented as percent transported as a function of time (means ± SD, n = 3). * Considered statistically significant (p<0.05).</p
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