Conservation of amino acids shown on the structure of AT1.

<p>View is from looking down the receptor from the extracellular surface<b>.</b> Red indicates amino acids commonly conserved in GPCRs, cyan those conserved with Rhodopsin, and green those conserved only in AT1, AT2 and MAS corresponding to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065307#pone-0065307-g004" target="_blank">Figure 4</a>. Amino acids shown are those identified in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065307#pone.0065307.s010" target="_blank">Table S1</a> to have functional roles in Ang peptides binding and activation of receptors, including the consensus GPCR number used.