Vaccine effectiveness of people of 15–64 y and 65 and over, of the epidemics between 1999 and 2011 (in percent) and mismatch between dominant or co-dominant circulating strains and vaccine strains.

<p>^a Because vaccine effectiveness (VE) for 2009–2010 and 2010–2011 epidemics were estimated using different vaccination coverage sources (administrative source <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065919#pone.0065919-Vaux1" target="_blank">[44]</a> and from GPs practices respectively) and strata (week for 2009–2010 and risk-group for influenza for 2010–2011 epidemic) we did not shown these VE estimated values in this study. ^b Indicate the viral dominant type or subtype when it differs from the vaccine strain for the season. Only mismatch with dominant type is considered. ‘–‘ indicate the circulating strains were close to the vaccine’s ones. ^c One of the 2 circulating A(H3N2) strains differed from the vaccine one.