<p>The figure displays the general mediation model that has been used to estimate effects according to path-diagrammatic conventions. Squares represent variables. <i>D<sub>i</sub></i> is one of the <i>p = 19</i> disorders under consideration, <i>M<sub>j</sub></i> is one of the <i>k = 8</i> mediating variables (disability dimensions), and VAS is the final outcome. Arrows represent regression slope parameters from independent variables to outcomes. The <i>δ</i> parameters stand for the direct effect regression from disorders to the final outcome. The <i>ι</i> parameters indicate the two regression components of the disorder indirect effects as mediated by <i>M</i>: a) <i>p</i> x <i>k</i> regression parameters from <i>D</i> to <i>M</i> (<i>ι<s...