Incidence and severity of <i>P. aeruginosa</i> infections in EDE mice.

<p>C57BL/6 mice were exposed to EDE or control conditions for 10 d prior to topical challenge with 10⁹ cfu of <i>P. aeruginosa</i> strain PAO1. Mice were monitored for corneal infiltrates, opacities, and changes in epithelial surface regularity. Pathology was graded at 96 h post-inoculation (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065797#s2" target="_blank">Materials and Methods</a>). Incidences of pathology in EDE and control groups were not significantly different (Chi-square analysis). Data is representative of two independent experiments.