Publication date
June 2013
DOIAbstract
<p>Tested single residue mutations based on grouping system. Residues shown in red indicate mutations that resulted in higher docking scores.</p
<p>Tested single residue mutations based on grouping system. Residues shown in red indicate mutations that resulted in higher docking scores.</p
<p>For each variant the relative activity at Aβ divided by the relative activity on the off target p...
<p>Mutations identified through whole-genome sequencing of TDZ resistant mutants.</p
<p>Comparison of the differences in the % of observed mutations in the 1 kG (blue) and OMIM (red) se...
Fig 3 depicts the graphical representation of mutations outcome and docking results of single mutati...
<p>Each cell counts the number of residue responses (ΔFI) that correspond to a given solvent accessi...
Scores for the 4 tested RNAs by A. Cléry et al. coloured in green for the RNAs that bind the target ...
S5 Table represents results of ΔΔG prediction of 71 single mutations displayed in terms of chain, wi...
<p>In each case the mutant structure refined by minimization is shown in cyan and the mutant structu...
Statistics of rays, antibody accessibility, and SASA scores in discriminating variant mutation sites...
<p>Mutational effects are shown as the Log of relative catalytic efficiency [(<i>k</i><sub>cat</sub>...
<p>Upon mutation, residues that result in a shift towards the “sharp” EPR spectrum are colored in ye...
Mutations occur either in any variable residues (All variable residues) or in the same residues that...
<p>(A) Sequence strength influenced by mutation of each single site. Red indicates positive mutation...
Single amino acid substitution is the type of protein alteration most related to human diseases. Cur...
<p>*the mutant efficiency was calculated by mutant colonies/total single cell colonies.</p
<p>For each variant the relative activity at Aβ divided by the relative activity on the off target p...
<p>Mutations identified through whole-genome sequencing of TDZ resistant mutants.</p
<p>Comparison of the differences in the % of observed mutations in the 1 kG (blue) and OMIM (red) se...
Fig 3 depicts the graphical representation of mutations outcome and docking results of single mutati...
<p>Each cell counts the number of residue responses (ΔFI) that correspond to a given solvent accessi...
Scores for the 4 tested RNAs by A. Cléry et al. coloured in green for the RNAs that bind the target ...
S5 Table represents results of ΔΔG prediction of 71 single mutations displayed in terms of chain, wi...
<p>In each case the mutant structure refined by minimization is shown in cyan and the mutant structu...
Statistics of rays, antibody accessibility, and SASA scores in discriminating variant mutation sites...
<p>Mutational effects are shown as the Log of relative catalytic efficiency [(<i>k</i><sub>cat</sub>...
<p>Upon mutation, residues that result in a shift towards the “sharp” EPR spectrum are colored in ye...
Mutations occur either in any variable residues (All variable residues) or in the same residues that...
<p>(A) Sequence strength influenced by mutation of each single site. Red indicates positive mutation...
Single amino acid substitution is the type of protein alteration most related to human diseases. Cur...
<p>*the mutant efficiency was calculated by mutant colonies/total single cell colonies.</p
<p>For each variant the relative activity at Aβ divided by the relative activity on the off target p...
<p>Mutations identified through whole-genome sequencing of TDZ resistant mutants.</p
<p>Comparison of the differences in the % of observed mutations in the 1 kG (blue) and OMIM (red) se...
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