<p>Combined with the GTR+I+Γ substitution model and Bayesian skyline coalesent model, the MCMC procedures were run under three clock models, exoponetial, lognormal, and strict, respectively, using BEAST. The vertical axis measures the substitution rate multiplied by 10<sup>−3</sup> (substitution/site/year). The horizontal axis indicates the nine genomic regions and the entire ORF. The left three panels show the results for the 1a dataset. The right three panels show the results for the 1b dataset. In each panel, two violins are separated in a small case on the right, which indicate the rates estimated for the routinely amplified partial Core-E1 (P-C/E1) and partial NS5B (P-NS5B) regions.</p
Phylogenetic analyses of DNA sequence data can provide estimates of evolutionary rates and timescale...
<p>Horizontal violin plots depict the distribution of minor allele frequencies (MAF) of the most str...
<p>Posterior distributions are summarized as the mode and boundaries of the 95% credibility interval...
<p>Panels A, B, and C show the median evolutionary rates. Panels D, E, and F show the median tMRCAs....
<p>Only patients for which samples for more than one time point are available were used for the with...
<p>The analysis was conducted using BEAST program. GTR model of substitution, lognormal relaxed cloc...
<p>Upper figure: Boxplot (left) and Densityplot of the MRCA posterior probability. Lower figure: Box...
Upper fig: Boxplot (left) and Densityplot of the MRCA posterior probability. Lower fig: Boxplot (lef...
<p>The mean evolutionary rate and highest posterior density (HPD) intervals are expressed as the num...
*<p>Estimates of the mean evolutionary rate (μ, substitutions.site<sup>−1</sup>.year<sup>−1</sup>) a...
Considerable progress has been made in the HCV evolutionary analysis, since the software BEAST was r...
a) Posterior distribution of substitution models. Each circle represents a substitution model indica...
<p>The width and color intensity of each violin plot is proportional to the increase in support (lik...
<p>(A) Effect sizes (<i>β</i>) on a log scale for each predictor were conditioned on the inclusion o...
<p>The within-host nonsynonymous (filled circles) and synonymous (open circles) substitution rates w...
Phylogenetic analyses of DNA sequence data can provide estimates of evolutionary rates and timescale...
<p>Horizontal violin plots depict the distribution of minor allele frequencies (MAF) of the most str...
<p>Posterior distributions are summarized as the mode and boundaries of the 95% credibility interval...
<p>Panels A, B, and C show the median evolutionary rates. Panels D, E, and F show the median tMRCAs....
<p>Only patients for which samples for more than one time point are available were used for the with...
<p>The analysis was conducted using BEAST program. GTR model of substitution, lognormal relaxed cloc...
<p>Upper figure: Boxplot (left) and Densityplot of the MRCA posterior probability. Lower figure: Box...
Upper fig: Boxplot (left) and Densityplot of the MRCA posterior probability. Lower fig: Boxplot (lef...
<p>The mean evolutionary rate and highest posterior density (HPD) intervals are expressed as the num...
*<p>Estimates of the mean evolutionary rate (μ, substitutions.site<sup>−1</sup>.year<sup>−1</sup>) a...
Considerable progress has been made in the HCV evolutionary analysis, since the software BEAST was r...
a) Posterior distribution of substitution models. Each circle represents a substitution model indica...
<p>The width and color intensity of each violin plot is proportional to the increase in support (lik...
<p>(A) Effect sizes (<i>β</i>) on a log scale for each predictor were conditioned on the inclusion o...
<p>The within-host nonsynonymous (filled circles) and synonymous (open circles) substitution rates w...
Phylogenetic analyses of DNA sequence data can provide estimates of evolutionary rates and timescale...
<p>Horizontal violin plots depict the distribution of minor allele frequencies (MAF) of the most str...
<p>Posterior distributions are summarized as the mode and boundaries of the 95% credibility interval...