Adriamycin-induced morphological changes in glomerular and tubular regions of the kidney.
- Kátia Daniela Silveira (419396)
- Lívia Corrêa Barroso (419397)
- Angélica Thomáz Vieira (419398)
- Daniel Cisalpino (161434)
- Cristiano Xavier Lima (419399)
- Michael Bader (135410)
- Rosa Maria Esteves Arantes (84397)
- Robson Augusto Souza dos Santos (419400)
- Ana Cristina Simões-e-Silva (419401)
- Mauro Martins Teixeira (419402)
Publication date
June 2013
DOIAbstract
<p>Representative photographs of PAS-stained glomerular and tubular regions noticed in control mice (Sham, A, B), and 7 (C, D), 14 (E, F) and 21 (G, H) days after injection of adriamycin (10 mg/kg). Glomerular damage (large arrows), tubule-interstitial changes, atrophy of tubular epithelial cells (arrowheads) and tubular enlargement (thin arrows, insert) increased in the renal cortex from day 7 (D) to day 14 (F, insert, arrow). Global sclerosis was observed in many glomeruli (E, asterisks). Resorption droplets were present in tubular cells at day 14 (panel F, thin arrows). Histological changes stabilized on day 21 (G, H). Original magnification 40× objective.</p
Add to ORKG