C57BL/6 mice are highly susceptible to diet induced hepatitis.

<p>(A) Liver leukocytes (CD45⁺ cells) were quantified in C57BL/6 (B6), BALB/c, and AKR mice fed either a standard diet (SD) or 4 weeks of lithogenic diet (LD) (*P<0.05 compared to SD controls, **P<0.05 compared to all groups; n = 3–5 per group). (B and E) H&E staining of liver from LD fed B6 mice under low and high power magnification respectively. Arrows in B point to inflammatory foci and E shows a representative inflammatory focus. (C and F) H&E staining of liver from LD fed AKR mice under low and high power magnification respectively. Oil-red-O staining showing lipid accumulation in BALB/c (G), B6 (H) and AKR mice (I) fed the LD but not in those fed the SD (J–L). Bars in B and C = 100µm; bars in D–L = 20µm.