<p>The <i>nfxB</i> mutations detected in the wild-type (WT) and mutator strains (<i>mutS</i>, <i>mutT</i>, <i>mutY</i> and <i>mutM</i>), and the WT strain after exposure to the mutagens 2-aminopurine (2AP), cisplatin (CPT) and hydrogen peroxide (HP) are summarized. The percentage of each mutation type relative to the total number of mutations detected for each strain or treatment is plotted using a color code.</p
Background: Genomic mutations caused by cytotoxic agents used in cancer chemotherapy may cause secon...
We have been quantitating, as a marker of cancer susceptibility, induced chromatid breaks in lymphoc...
<p>The curves represent the change in number of viable cells (log scale) over time at different conc...
a<p>Mutation rates (<i>µ</i>) per replication and 95% confidence limits (CL) were calculated as desc...
nfxB encodes a negative regulator of the mexCD-oprJ genes for drug efflux in the opportunistic patho...
nfxB encodes a negative regulator of the mexCD-oprJ genes for drug efflux in the opportunistic patho...
<div><p><i>nfxB</i> encodes a negative regulator of the <i>mexCD-oprJ</i> genes for drug efflux in t...
<p>Results for all INH-resistant strains are grouped, as well as the results for are wildtype strain...
<p>The position of all mutations detected in <i>nfxB</i> among 240 Cip<sup>r</sup> clones derived in...
We describe how mutant yield data (mutants per cell treated) can be used both to compare the mutagen...
Mutation frequency measurement experiments were set up in such a way that each individual culture ha...
<p>H<sub>2</sub>O<sub>2</sub>-induced mutagenesis was measured in <i>mutS<sup>+</sup></i> (<b>A</b>)...
Mechanisms by which carcinogens induce mutations in human cells can be investigated using carcinogen...
A study of the alteration of the DNA in the mutant gene can determine mechanisms of mutation by dist...
A. Spectra of mutations identified by Sanger sequencing of CanR Red isolates in the triple subtelome...
Background: Genomic mutations caused by cytotoxic agents used in cancer chemotherapy may cause secon...
We have been quantitating, as a marker of cancer susceptibility, induced chromatid breaks in lymphoc...
<p>The curves represent the change in number of viable cells (log scale) over time at different conc...
a<p>Mutation rates (<i>µ</i>) per replication and 95% confidence limits (CL) were calculated as desc...
nfxB encodes a negative regulator of the mexCD-oprJ genes for drug efflux in the opportunistic patho...
nfxB encodes a negative regulator of the mexCD-oprJ genes for drug efflux in the opportunistic patho...
<div><p><i>nfxB</i> encodes a negative regulator of the <i>mexCD-oprJ</i> genes for drug efflux in t...
<p>Results for all INH-resistant strains are grouped, as well as the results for are wildtype strain...
<p>The position of all mutations detected in <i>nfxB</i> among 240 Cip<sup>r</sup> clones derived in...
We describe how mutant yield data (mutants per cell treated) can be used both to compare the mutagen...
Mutation frequency measurement experiments were set up in such a way that each individual culture ha...
<p>H<sub>2</sub>O<sub>2</sub>-induced mutagenesis was measured in <i>mutS<sup>+</sup></i> (<b>A</b>)...
Mechanisms by which carcinogens induce mutations in human cells can be investigated using carcinogen...
A study of the alteration of the DNA in the mutant gene can determine mechanisms of mutation by dist...
A. Spectra of mutations identified by Sanger sequencing of CanR Red isolates in the triple subtelome...
Background: Genomic mutations caused by cytotoxic agents used in cancer chemotherapy may cause secon...
We have been quantitating, as a marker of cancer susceptibility, induced chromatid breaks in lymphoc...
<p>The curves represent the change in number of viable cells (log scale) over time at different conc...