Knockdown of downstream mediators of semaphorin signaling, Cdk5 and FAK, induced defective dendritic morphologies of newborn DGCs in adult brain.

<p>(A) Representative images and tracings of dendrites of control, Cdk5 or FAK-shRNA expressing DGCs at 14 dpi (Scale bar, 20 µm). Graphs showing quantification of total dendritic length (B) and branch number (C) of newborn DGCs. Each symbol represents a single DGC at 14 dpi. (**P<0.01, 1-way ANOVA with Newman-Keuls’ post-hoc test).