Based on results of a meta-analysis of risk association of type 2 diabetes (T2D) in 9,901 Asian subjects with <i>de novo</i> genotyping, each risk allele of rs1583645 (<i>CPE</i>) and rs6583813 (<i>IDE</i>) was given a genetic risk scores (GRS) of 1 under additive models.
- Vincent Kwok Lim Lam (246186)
- Ronald Ching Wan Ma (246193)
- Heung Man Lee (246184)
- Cheng Hu (44938)
- Kyong Soo Park (172819)
- Hiroto Furuta (420414)
- Ying Wang (11406)
- Claudia Ha Ting Tam (246178)
- Xueling Sim (103662)
- Daniel Peng-Keat Ng (225337)
- Jianjun Liu (28194)
- Tien-Yin Wong (159436)
- E. Shyong Tai (103763)
- Andrew P. Morris (145709)
- Nelson Leung Sang Tang (364293)
- Jean Woo (240342)
- Ping Chung Leung (420415)
- Alice Pik Shan Kong (420416)
- Risa Ozaki (420417)
- Wei Ping Jia (420418)
- Hong Kyu Lee (179212)
- Kishio Nanjo (420419)
- Gang Xu (219455)
- Maggie Chor Yin Ng (246198)
- Wing-Yee So (85297)
- Juliana Chung Ngor Chan (246195)
Publication date
June 2013
DOIAbstract
<p>Increasing GRS was associated with increasing trend of risk for T2D (<i>P</i><sub>meta</sub> = 0.01; Q-statistic <i>P</i><0.05) with the highest GRS of 4 conferring an odds ratios of 1.56 compared to the lowest GRS of 0 (*<i>P</i> = 0.01).</p
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