Representative immunohistochemical analysis using the TUSC1 antibody in normal and primary lung tissues.

<p>(A) Bronchioepithelium of Normal Lung. The basal layer was not positive for TUSC1 but differentiated cells in the upper layers of epithelium have high TUSC1 expression. Distribution of TUSC1 staining was cytoplasmic, nuclear and nuclear/cytoplasmic in the cells. (B, C) Lung cancer tissue microarray stained with <i>TUSC1</i> antibody and representative tissue cores (1–3) for each level of staining intensity. (D–F) Kaplan-Meier survival plots for the overall patient (D), adenocarcinoma (E) and squamous cell carcinoma (F). Survival status and the associated <i>P</i> value are indicated. Red line represents tumors with higher expression levels of <i>TUSC1</i> (score: 3), green line represents tumor with lower expression levels of <i>TUSC1</i> (score: 0–2).