TUNEL staining showed that DC260126 reduced the number of apoptotic pancreatic β-cells.

<p>(A) The TUNEL positive cells were marked with dark brown in nucleis, and the sections were stained with methyl green, the scale bar = 100 µm, and referred to all panels. (B) The number of TUNEL-positive cells was counted and divide with the area of each islet. At least 5 islets on each section from animals in the three groups were analyzed. ***<i>p</i><0.001 v.s. lean group, and ## <i>p</i><0.01 indicated significant differences between vehicle and DC260126-treated group.