<p>We found 339 genes that were differentially expressed in female nonagenarians, compared to young female controls, and 248 genes that were differentially expressed in male nonagenarians, compared to young male controls (p<0.05, −1.5> FC >1.5). A total of 180 of these genes were common to both genders. Slightly more genes were up-regulated (1b) than were down-regulated (1c) in the nonagenarians of both genders.</p
*<p>Gene names were obtained from <a href="http://flybase.org" target="_blank">http://flybase.org</a...
Human regulatory variation, reported as expression quantitative trait loci (eQTLs), contributes to d...
<p>(A) Proportion of male-biased and female-biased genes for autosomes, LG9, and LG19. (B) No signif...
BACKGROUND: Despite their nearly identical genomes, males and females differ in risk, incidence, pre...
<p>The pie charts (A, B) show the number of differentially expressed genes between the <i>him-8 GFP<...
Background: Despite their nearly identical genomes, males and females differ in risk, incidence, pre...
<p>P-values were derived from Fisher’s exact test, -log(0.05) = 1.3, and the Benjamini-Hochberg-corr...
Many complex human phenotypes exhibit sex-differentiated characteristics. However, the molecular mec...
Human regulatory variation, reported as expression quantitative trait loci (eQTLs), contributes to d...
Abstract Background Sex is an important but understudied factor in the genetics of human diseases. A...
Background: Genomes of men and women differ in only a limited number of genes located on the sex chr...
The severity and prevalence of many diseases are known to differ between the sexes. Organ specific s...
Aging and gender have a strong influence on the functional capacity of the immune system. In general...
<p>The pathways that were significant only in females are shown. The p-values were derived from Fish...
Aging and gender have a strong influence on the functional capacity of the immune system. In general...
*<p>Gene names were obtained from <a href="http://flybase.org" target="_blank">http://flybase.org</a...
Human regulatory variation, reported as expression quantitative trait loci (eQTLs), contributes to d...
<p>(A) Proportion of male-biased and female-biased genes for autosomes, LG9, and LG19. (B) No signif...
BACKGROUND: Despite their nearly identical genomes, males and females differ in risk, incidence, pre...
<p>The pie charts (A, B) show the number of differentially expressed genes between the <i>him-8 GFP<...
Background: Despite their nearly identical genomes, males and females differ in risk, incidence, pre...
<p>P-values were derived from Fisher’s exact test, -log(0.05) = 1.3, and the Benjamini-Hochberg-corr...
Many complex human phenotypes exhibit sex-differentiated characteristics. However, the molecular mec...
Human regulatory variation, reported as expression quantitative trait loci (eQTLs), contributes to d...
Abstract Background Sex is an important but understudied factor in the genetics of human diseases. A...
Background: Genomes of men and women differ in only a limited number of genes located on the sex chr...
The severity and prevalence of many diseases are known to differ between the sexes. Organ specific s...
Aging and gender have a strong influence on the functional capacity of the immune system. In general...
<p>The pathways that were significant only in females are shown. The p-values were derived from Fish...
Aging and gender have a strong influence on the functional capacity of the immune system. In general...
*<p>Gene names were obtained from <a href="http://flybase.org" target="_blank">http://flybase.org</a...
Human regulatory variation, reported as expression quantitative trait loci (eQTLs), contributes to d...
<p>(A) Proportion of male-biased and female-biased genes for autosomes, LG9, and LG19. (B) No signif...