Time course of adiponectin level in the explants incubation medium and serum.

<p>At the age of 5w, 6w and 7w, adiponectin level in the explants incubation medium (EIM) of the db/db mice was significantly lower than that of lean mice(P<0.01) (Fig. 8A), indicating that adiponectin production from the epididymal adipose tissue was decreased in db/db mice; Adiponectin in the serum was comparable between db/db mice and lean mice at each point (Fig. 8B).