Deformed structure and delayed elevation of palatal shelves in <i>Wnt1Cre</i>;<i>capMes</i>-<i>caBmprIa</i> mice.

<p>(A–C) Coronal sections of E13.5 control and <i>Wnt1Cre</i>;<i>pMes</i>-<i>caBmprIa</i> embryos show deformed morphology of palatal shelves in transgenic animals. Note the presence of ectopic condensed cell masses (arrows) within in the posterior palatal shelves of the transgenic embryo (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0066107#pone-0066107-g002" target="_blank">Fig. 2D</a>). (E–H) Coronal sections of E14.5 wild type and <i>Wnt1Cre</i>;<i>pMes</i>-<i>caBmprIa</i> embryos show delayed elevation of palatal shelves in transgenic animal. M, Meckel's cartilage; T, tongue; PS, palatal shelf. Scale bar = 500 µm.