<p>Phylogram showing the relationship between bacterial and protozoan homologues of MscS and MscK channel subunits (<i>see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0066068#s3" target="_blank">Methods</a></i>: based on 113 high-confidence positions from a multiple sequence alignment; gamma shape parameter 3.83; proportion of invariant sites 0). Homologues from different groups of organisms are indicated. Branch length scale bar (amino acid substitutions per site) and branch support values >0.5 are shown.</p
<p>The EngA protein from <i>Mycoplasma</i> mobile strain K163 was included. Conserved amino acids pr...
<p><b>A</b>) Amino acid sequence alignment of several SNXs from different species where the domain b...
<p>A, Amino acid alignment of both SmPKA-C and putative splice variant peptide sequences with PKA-C ...
<p>Phylogram showing the relationship between homologues of Piezo channel subunits (<i>see <a href="...
<p>Multiple sequence alignment of MscS homologues from <i>Escherichia coli</i> and trypanosomatid pa...
<p>(<b>A</b>) Predicted topology of MCU channels, with the putative pore loop indicated; (<b>B</b>) ...
<p>Protein accession numbers are shown and NF denotes that no homologues were found. Number of predi...
<p>Protein accession numbers for homologues are shown and the number of predicted transmembrane doma...
<p>Phylogram showing the relationship between the sequences of fungal and human K<sup>+</sup> channe...
<p>Predicted pore-lining TMD regions are underlined. The GXG motif of human K<sup>+</sup> channels i...
<div><p>Mechanosensitive channels play important roles in the physiology of many organisms, and thei...
<p>Locations of predicted transmembrane domains (TMDs) and conserved motifs in the homologues of Pie...
<p>(A) Alignments of pore domains I (upper panel) and II (lower panel) of human, plant (AtTPC1 is <i...
<p>(<b>A</b>) Phylogram showing the relationship between the sequences of human K<sub>Ca</sub> chann...
<p>(A) Sequence comparison of the archeal mechanosensitive channels T1 and T2 from <i>Thermoplasma v...
<p>The EngA protein from <i>Mycoplasma</i> mobile strain K163 was included. Conserved amino acids pr...
<p><b>A</b>) Amino acid sequence alignment of several SNXs from different species where the domain b...
<p>A, Amino acid alignment of both SmPKA-C and putative splice variant peptide sequences with PKA-C ...
<p>Phylogram showing the relationship between homologues of Piezo channel subunits (<i>see <a href="...
<p>Multiple sequence alignment of MscS homologues from <i>Escherichia coli</i> and trypanosomatid pa...
<p>(<b>A</b>) Predicted topology of MCU channels, with the putative pore loop indicated; (<b>B</b>) ...
<p>Protein accession numbers are shown and NF denotes that no homologues were found. Number of predi...
<p>Protein accession numbers for homologues are shown and the number of predicted transmembrane doma...
<p>Phylogram showing the relationship between the sequences of fungal and human K<sup>+</sup> channe...
<p>Predicted pore-lining TMD regions are underlined. The GXG motif of human K<sup>+</sup> channels i...
<div><p>Mechanosensitive channels play important roles in the physiology of many organisms, and thei...
<p>Locations of predicted transmembrane domains (TMDs) and conserved motifs in the homologues of Pie...
<p>(A) Alignments of pore domains I (upper panel) and II (lower panel) of human, plant (AtTPC1 is <i...
<p>(<b>A</b>) Phylogram showing the relationship between the sequences of human K<sub>Ca</sub> chann...
<p>(A) Sequence comparison of the archeal mechanosensitive channels T1 and T2 from <i>Thermoplasma v...
<p>The EngA protein from <i>Mycoplasma</i> mobile strain K163 was included. Conserved amino acids pr...
<p><b>A</b>) Amino acid sequence alignment of several SNXs from different species where the domain b...
<p>A, Amino acid alignment of both SmPKA-C and putative splice variant peptide sequences with PKA-C ...