DNase I Hypersensitive sites at the α globin cluster on chromosome 11.

<p><b>a</b>) Chromosomal positions in Kb on chromosome 11 are shown for MGSC37 mouse reference genome. The names of previously annotated <i>DNaseI</i> hypersensitive sites (DHS) are shown coloured as ubiquitous (green), erythroid (red) and black (CTCF) <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003570#pgen.1003570-Kowalczyk1" target="_blank">[15]</a>. Two previously unpublished DHS (marked *) are associated with CTCF binding sites. The density of aligned DHS-seq reads in a moving 300 bp window, with a 30 bp increment is shown for each mouse strain. DHS-seq peaks are aligned with the position of each previously described DHS by dashed lines, colour coded as described. The position of Refseq annotated genes are named and shown below in blue. <b>b</b>) Two examples of DHS-seq biological replicates for the C57BL/6J and CBA/J strains are shown over the same region as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003570#pgen-1003570-g001" target="_blank">Figure 1a</a>.