Brain regions that showed significant activation during passive right hand movement within each of the 3 study groups.

Significant hemisphere-specific cerebral activation patterns during movement execution in the affected hand for patients, feigners, and normal controls.

Marije van Beilen (5652724)
Bauke M. de Jong (314815)
Esther W. Gieteling (341230)
Remco Renken (331558)
Klaus L. Leenders (314814)

February 2013

Unflipped data for movement execution in the affected hand is shown for (A) patients versus norma...

Plots of contrast estimates of brain activity in three groups of subjects: healthy controls (HC), relapsing-remitting (RRMS) MS patients and secondary progressive (SPMS) MS patients, centered on the activity peaks of the average effect of conditions (activation in red, deactivation in blue) by ANOVA (p<0.05 FWE corrected at cluster level).

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

Plots show that significant differences in brain activation between groups in the left precentral...

Cerebral activation in within-group comparison Affected versus Unaffected* in patients and feigners) side during movement execution.

Marije van Beilen (5652724)
Bauke M. de Jong (314815)
Esther W. Gieteling (341230)
Remco Renken (331558)
Klaus L. Leenders (314814)

February 2013

Coordinates refer to the voxels of maximum activation within significant clusters (P<0.05, whole-...

Brain regions that showed significant deactivation during passive right hand movement within each of the three groups.

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

L = left; R = Right; Bi = Bilateral; MNI = Montreal Neurological Institute.HC = Healthy Co...

Brain regions that showed significant differences between groups in activation (red) and deactivation (blue) during passive right hand movement.

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

Maps obtained by two sample t-test, corrected for age and gender at p<0.05 FWE (cluster level) ar...

Brain regions that showed significant activation (red) and deactivation (blue) during passive right hand movement in three groups of subjects: healthy controls (HC), relapsing-remitting MS patients (RRMS) and secondary progressive MS patients (SPMS).

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

Maps obtained by one sample t-test, corrected for age and gender at p<0.05 FWE (cluster level) ar...

Evidence of Impaired Brain Activity Balance after Passive Sensorimotor Stimulation in Multiple Sclerosis

Nikolaos Petsas
Emanuele Tinelli
Delia Lenzi
Valentina Tomassini
Emilia Sbardella
Francesca Tona
Eytan Raz
Valter Nucciarelli
Carlo Pozzilli
Patrizia Pantano

August 2016

Objectives: Examination of sensorimotor activation alone in multiple sclerosis (MS) patients may not...

Impairment of movement-associated brain deactivation in multiple sclerosis: further evidence for a functional pathology of interhemispheric neuronal inhibition

MANSON SC
WEGNER C
FILIPPI M
BARKHOF F
BECKMANN C
CICCARELLI O
ENZINGER C
FAZEKAS F
AGOSTA F
GASS A
HIRSCH J
JOHANSEN BERG H
KAPPOS L
KORTEWEG T
POLMAN C
MANCINI L
MANFREDONIA F
MARINO S
MILLER DH
MONTALBAN X
PALACE J
ROCCA M
ROPELE S
ROVIRA A
SMITH S
THOMPSON A
THORNTON J
YOUSRY T
FRANK JA
MATTHEWS PM
DE STEFANO, NICOLA

January 2008

Motor control demands coordinated excitation and inhibition across distributed brain neuronal networ...

Impairment of movement-associated brain deactivation in multiple sclerosis: further evidence for a functional pathology of interhemispheric neuronal inhibition.

Manson, SC
Wegner, C
Filippi, M
Barkhof, F
Beckmann, C
Ciccarelli, O
De Stefano, N
Enzinger, C
Fazekas, F
Agosta, F
Gass, A
Hirsch, J
Johansen-Berg, H
Kappos, L
Korteweg, T
Polman, C
Mancini, L
Manfredonia, F
Marino, S
Miller, DH
Montalban, X
Palace, J
Rocca, M
Ropele, S
Rovira, A
Smith, S
Thompson, A
Thornton, J
Yousry, T
Frank, JA
Matthews, PM

May 2008

Motor control demands coordinated excitation and inhibition across distributed brain neuronal networ...

Evidence of impaired brain activity balance after passive sensorimotor stimulation in multiple sclerosis

Petsas, Nikolaos
Tinelli, Emanuele
Lenzi, Delia
Tomassini, Valentina
Sbardella, Emilia
Tona, Francesca
Raz, Eytan
Nucciarelli, Valter
Pozzilli, Carlo
Pantano, Patrizia

June 2013

Objectives Examination of sensorimotor activation alone in multiple sclerosis (MS) patients may n...

A multicentre study of motor functional connectivity changes in patients with multiple sclerosis

VALSASINA P
ROCCA MA
ABSINTA M
SORMANI MP
MANCINI L
N. DE STEFANO
ROVIRA A
GASS A
ENZINGER C
BARKHOF F
WEGNER C
MATTHEWS PM
FILIPPI M

January 2011

In this multicentre study involving eight European centres, we characterized the spatial pattern of ...

Relating functional changes during hand movement to clinical parameters in patients with multiple sclerosis in a multi-centre fMRI study

WEGNER C
FILIPPI M
BARKHOF F
BECKMANN C
CICCARELLI O
N. DE STEFANO
ENZINGER C
FAZEKAS F
AGOSTA F
GASS A
HIRSCH J
JOHANSEN-BERG H
KAPPOS L
KORTEWEG T
POLMAN C
MANCINI L
MANFREDONIA F
MARINO S
MILLER DH
MONTALBAN X
PALACE J
ROCCA M
ROPELE S
ROVIRA A
SMITH S
THOMPSON A
THORNTON J
YOUSRY T
MATTHEWS PM

January 2008

We performed a prospective multi-centre study using functional magnetic resonance imaging (fMRI) to ...

Impaired cortical deactivation during hand movement in the relapsing phase of multiple sclerosis: a cross-sectional and longitudinal fMRI study

Patrizia Pantano
Silvia Bernardi
Emanuele Tinelli
Simona Pontecorvo
Delia Lenzi
Eytan Raz
Francesca Tona
C. Gasperini
Carlo Pozzilli

January 2011

Background: Little is known about the cortical activation changes during clinical relapses in multip...

Relating functional changes during hand movement to clinical parameters in patients with multiple sclerosis in a multi-centre fMRI study.

Wegner, C
Filippi, M
Korteweg, T
Beckmann, C
Ciccarelli, O
De Stefano, N
Enzinger, C
Fazekas, F
Agosta, F
Gass, A
Hirsch, J
Johansen-Berg, H
Kappos, L
Barkhof, F
Polman, C
Mancini, L
Manfredonia, F
Marino, S
Miller, DH
Montalban, X
Palace, J
Rocca, M
Ropele, S
Rovira, A
Smith, S
Thompson, A
Thornton, J
Yousry, T
Matthews, PM

February 2008

We performed a prospective multi-centre study using functional magnetic resonance imaging (fMRI) to ...

Investigation of the neural correlates underlying action observation in multiple sclerosis patients

Pierno, ANDREA CRISTIANO
Turella, L
Grossi, P
Tubaldi, Federico
Calabrese, Massimiliano
Perini, Paola
Barachino, L
Morra, A
Gallo, Paolo
Castiello, Umberto

January 2009

Recent fMRI evidence indicates that both the execution and the observation of hand actions in multip...

Significant hemisphere-specific cerebral activation patterns during movement execution in the affected hand for patients, feigners, and normal controls.

Marije van Beilen (5652724)
Bauke M. de Jong (314815)
Esther W. Gieteling (341230)
Remco Renken (331558)
Klaus L. Leenders (314814)

February 2013

Unflipped data for movement execution in the affected hand is shown for (A) patients versus norma...

Plots of contrast estimates of brain activity in three groups of subjects: healthy controls (HC), relapsing-remitting (RRMS) MS patients and secondary progressive (SPMS) MS patients, centered on the activity peaks of the average effect of conditions (activation in red, deactivation in blue) by ANOVA (p<0.05 FWE corrected at cluster level).

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

Plots show that significant differences in brain activation between groups in the left precentral...

Cerebral activation in within-group comparison Affected versus Unaffected* in patients and feigners) side during movement execution.

Marije van Beilen (5652724)
Bauke M. de Jong (314815)
Esther W. Gieteling (341230)
Remco Renken (331558)
Klaus L. Leenders (314814)

February 2013

Coordinates refer to the voxels of maximum activation within significant clusters (P<0.05, whole-...

Brain regions that showed significant deactivation during passive right hand movement within each of the three groups.

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

L = left; R = Right; Bi = Bilateral; MNI = Montreal Neurological Institute.HC = Healthy Co...

Brain regions that showed significant differences between groups in activation (red) and deactivation (blue) during passive right hand movement.

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

Maps obtained by two sample t-test, corrected for age and gender at p<0.05 FWE (cluster level) ar...

Brain regions that showed significant activation (red) and deactivation (blue) during passive right hand movement in three groups of subjects: healthy controls (HC), relapsing-remitting MS patients (RRMS) and secondary progressive MS patients (SPMS).

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

Maps obtained by one sample t-test, corrected for age and gender at p<0.05 FWE (cluster level) ar...

Evidence of Impaired Brain Activity Balance after Passive Sensorimotor Stimulation in Multiple Sclerosis

Nikolaos Petsas
Emanuele Tinelli
Delia Lenzi
Valentina Tomassini
Emilia Sbardella
Francesca Tona
Eytan Raz
Valter Nucciarelli
Carlo Pozzilli
Patrizia Pantano

August 2016

Objectives: Examination of sensorimotor activation alone in multiple sclerosis (MS) patients may not...

Impairment of movement-associated brain deactivation in multiple sclerosis: further evidence for a functional pathology of interhemispheric neuronal inhibition

MANSON SC
WEGNER C
FILIPPI M
BARKHOF F
BECKMANN C
CICCARELLI O
ENZINGER C
FAZEKAS F
AGOSTA F
GASS A
HIRSCH J
JOHANSEN BERG H
KAPPOS L
KORTEWEG T
POLMAN C
MANCINI L
MANFREDONIA F
MARINO S
MILLER DH
MONTALBAN X
PALACE J
ROCCA M
ROPELE S
ROVIRA A
SMITH S
THOMPSON A
THORNTON J
YOUSRY T
FRANK JA
MATTHEWS PM
DE STEFANO, NICOLA

January 2008

Motor control demands coordinated excitation and inhibition across distributed brain neuronal networ...

Impairment of movement-associated brain deactivation in multiple sclerosis: further evidence for a functional pathology of interhemispheric neuronal inhibition.

Manson, SC
Wegner, C
Filippi, M
Barkhof, F
Beckmann, C
Ciccarelli, O
De Stefano, N
Enzinger, C
Fazekas, F
Agosta, F
Gass, A
Hirsch, J
Johansen-Berg, H
Kappos, L
Korteweg, T
Polman, C
Mancini, L
Manfredonia, F
Marino, S
Miller, DH
Montalban, X
Palace, J
Rocca, M
Ropele, S
Rovira, A
Smith, S
Thompson, A
Thornton, J
Yousry, T
Frank, JA
Matthews, PM

May 2008

Motor control demands coordinated excitation and inhibition across distributed brain neuronal networ...

Evidence of impaired brain activity balance after passive sensorimotor stimulation in multiple sclerosis

Petsas, Nikolaos
Tinelli, Emanuele
Lenzi, Delia
Tomassini, Valentina
Sbardella, Emilia
Tona, Francesca
Raz, Eytan
Nucciarelli, Valter
Pozzilli, Carlo
Pantano, Patrizia

June 2013

Objectives Examination of sensorimotor activation alone in multiple sclerosis (MS) patients may n...

A multicentre study of motor functional connectivity changes in patients with multiple sclerosis

VALSASINA P
ROCCA MA
ABSINTA M
SORMANI MP
MANCINI L
N. DE STEFANO
ROVIRA A
GASS A
ENZINGER C
BARKHOF F
WEGNER C
MATTHEWS PM
FILIPPI M

January 2011

In this multicentre study involving eight European centres, we characterized the spatial pattern of ...

Relating functional changes during hand movement to clinical parameters in patients with multiple sclerosis in a multi-centre fMRI study

WEGNER C
FILIPPI M
BARKHOF F
BECKMANN C
CICCARELLI O
N. DE STEFANO
ENZINGER C
FAZEKAS F
AGOSTA F
GASS A
HIRSCH J
JOHANSEN-BERG H
KAPPOS L
KORTEWEG T
POLMAN C
MANCINI L
MANFREDONIA F
MARINO S
MILLER DH
MONTALBAN X
PALACE J
ROCCA M
ROPELE S
ROVIRA A
SMITH S
THOMPSON A
THORNTON J
YOUSRY T
MATTHEWS PM

January 2008

We performed a prospective multi-centre study using functional magnetic resonance imaging (fMRI) to ...

Impaired cortical deactivation during hand movement in the relapsing phase of multiple sclerosis: a cross-sectional and longitudinal fMRI study

Patrizia Pantano
Silvia Bernardi
Emanuele Tinelli
Simona Pontecorvo
Delia Lenzi
Eytan Raz
Francesca Tona
C. Gasperini
Carlo Pozzilli

January 2011

Background: Little is known about the cortical activation changes during clinical relapses in multip...

Relating functional changes during hand movement to clinical parameters in patients with multiple sclerosis in a multi-centre fMRI study.

Wegner, C
Filippi, M
Korteweg, T
Beckmann, C
Ciccarelli, O
De Stefano, N
Enzinger, C
Fazekas, F
Agosta, F
Gass, A
Hirsch, J
Johansen-Berg, H
Kappos, L
Barkhof, F
Polman, C
Mancini, L
Manfredonia, F
Marino, S
Miller, DH
Montalban, X
Palace, J
Rocca, M
Ropele, S
Rovira, A
Smith, S
Thompson, A
Thornton, J
Yousry, T
Matthews, PM

February 2008

We performed a prospective multi-centre study using functional magnetic resonance imaging (fMRI) to ...

Investigation of the neural correlates underlying action observation in multiple sclerosis patients

Pierno, ANDREA CRISTIANO
Turella, L
Grossi, P
Tubaldi, Federico
Calabrese, Massimiliano
Perini, Paola
Barachino, L
Morra, A
Gallo, Paolo
Castiello, Umberto

January 2009

Recent fMRI evidence indicates that both the execution and the observation of hand actions in multip...

Significant hemisphere-specific cerebral activation patterns during movement execution in the affected hand for patients, feigners, and normal controls.

Marije van Beilen (5652724)
Bauke M. de Jong (314815)
Esther W. Gieteling (341230)
Remco Renken (331558)
Klaus L. Leenders (314814)

February 2013

Unflipped data for movement execution in the affected hand is shown for (A) patients versus norma...

Plots of contrast estimates of brain activity in three groups of subjects: healthy controls (HC), relapsing-remitting (RRMS) MS patients and secondary progressive (SPMS) MS patients, centered on the activity peaks of the average effect of conditions (activation in red, deactivation in blue) by ANOVA (p<0.05 FWE corrected at cluster level).

Nikolaos Petsas (413156)
Emanuele Tinelli (422096)
Delia Lenzi (422097)
Valentina Tomassini (422098)
Emilia Sbardella (413155)
Francesca Tona (413157)
Eytan Raz (413159)
Valter Nucciarelli (422099)
Carlo Pozzilli (413161)
Patrizia Pantano (413162)

June 2013

Plots show that significant differences in brain activation between groups in the left precentral...

Cerebral activation in within-group comparison Affected versus Unaffected* in patients and feigners) side during movement execution.

Marije van Beilen (5652724)
Bauke M. de Jong (314815)
Esther W. Gieteling (341230)
Remco Renken (331558)
Klaus L. Leenders (314814)

February 2013

Coordinates refer to the voxels of maximum activation within significant clusters (P<0.05, whole-...

Brain regions that showed significant activation during passive right hand movement within each of the 3 study groups.

Abstract

Extracted data

Brain regions that showed significant activation during passive right hand movement within each of the 3 study groups.

Abstract

Extracted data

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