Yo positive serum containing CDR2L stains Purkinje cells.

<p>Serum from a patient with PCD and Yo antibodies (both anti-CDR2 and anti-CDR2L) shows granular cytoplasmic staining of Purkinje cells in rat cerebellar section (A). Similar staining of the serum was observed after absorption with recombinant CDR2 (B). However, no staining was observed when the serum was absorbed with recombinant CDR2L (C). Scale bar 10 µm.