Skin properties under compression measured across weight, hair cycle and skin location.

<p>Body weight for mature mice plotted versus skin thickness (<b>A</b>), stiffness (<b>B</b>) and elastic modulus (<b>C</b>). Linear regression (dotted lines) indicate that body weight is significantly correlated with skin thickness (r = 0.793, p-value<10⁻⁶), inversely correlated with skin stiffness (r = −0.717, p-value<10⁻³) and uncorrelated with modulus. Skin mechanical parameters are shown with respect to hair cycle stages (<b>D–F</b>) and skin site (<b>G–I)</b>. Statistical significance was assessed by Pearson test of correlation and unpaired Student's <i>t</i> test and results are given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0067439#pone-0067439-t001" target="_blank">Tables 1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0067439#pone-0067439-t002" target="_blank">2</a>. For all plots, boxes range from lower to upper quartiles, red lines within boxes indicate medians, black lines outside of boxes indicate max. and min. values and red (+) indicate outliers beyond 1.5 interquartile range.