Effect of CDRI-85/287 on tumor regression in MDA-MB 231 xenograft mouse model.
- Ruchi Saxena (423566)
- Vishal Chandra (423567)
- Murli Manohar (423568)
- Kanchan Hajela (423569)
- Utsab Debnath (423570)
- Yenamandra S. Prabhakar (423571)
- Karan Singh Saini (423572)
- Rituraj Konwar (423573)
- Sandeep Kumar (145759)
- Kaling Megu (423574)
- Bal Gangadhar Roy (423575)
- Anila Dwivedi (423576)
Publication date
June 2013
DOIAbstract
<p>(A) Representative images of MDA-MB 231 xenograft nude mice showing regression in tumor volume after treatment with CDRI-85/287(10 mg/kg, p.o.) in comparison to vehicle treated (VT) group. (B) Upper panel shows the dissected out tumors from vehicle treated and CDRI-85/287 treated xenograft mice. Lower panel shows representative images of hematoxylin and eosin stained tissue sections from vehicle- and CDRI-85/287 treated groups. (C) Graph showing tumor volume changes within 16 days after initiation of treatment (marked by arrow). Number of animals per group = 6 to 8. (D) The average body weights of the mice during tumor development and treatment (marked by arrow). Number of animals per group = 6 to 8.</p
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