Phylogenetic dendrogram based on comparisons of different genomic regions of the 21 prototype strains and 20 modern strains (including isolates) in HEV-B species using MEGA (version 5.0) and the maximum-likelihood method.

<p>(a) P1 region; (b) VP1 region; (c) P2 region; (d) P3 region. Bootstrap values (percentage of 1000 pseudo-replicate data sets) >70% were omitted for clarity. EV71 was used as outgroup in each tree. •Isolates sequenced in this investigation; △closest strains; ○prototype strains; ▴recombination strains.