<div><p>Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate expression of a number of genes associated with the cellular differentiation and development. Here, we show the abundant and ubiquitous expression of a newly identified splicing variant of mouse <i>Pparγ</i> (<i>Pparγ1sv</i>) that encodes PPARγ1 protein, and its importance in adipogenesis. The novel splicing variant has a unique 5′-UTR sequence, relative to those of <i>Pparγ1</i> and <i>Pparγ2</i> mRNAs, indicating the presence of a novel transcriptional initiation site and promoter for <i>Pparγ</i> expression. <i>Pparγ1sv</i> was highly expressed in the white and brown adipose tissues at levels comparable to <i>Pparγ2</i>. <i>Pparγ1sv</i> was sy...
<p>Real-time qPCR analysis of <i>LacZ</i> (<b>A</b>), PPARγ (<b>B</b>), and adiponectin (<b>C</b>) e...
AbstractAdipocyte differentiation is controlled by a tightly regulated transcriptional cascade in wh...
Abstract Background Adipose tissues serve not only as a store for energy in the form of lipid, but a...
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate expression o...
Peroxisome-proliferator-activated receptor γ (PPARγ) regulates glucose and lipid homeostasis, insuli...
<div><p>Adipose tissue renewal and obesity-driven expansion of fat cell number are dependent on prol...
Adipose tissue renewal and obesity-driven expansion of fat cell number are dependent on proliferatio...
The nuclear receptor PPARγ is a key regulator of adipogenesis, and alterations of its function are a...
International audienceThe nuclear receptor peroxisome proliferator-activated receptor (PPAR) is a tr...
The nuclear receptor PPAR γ is a key regulator of adipogenesis, and alterations of its function are ...
The nuclear receptor PPAR γ is a key regulator of adipogenesis, and alterations of its function are ...
AbstractPeroxisome proliferator-activated receptor (PPAR) γ was shown to be required for adipocyte f...
Pyruvate carboxylase (PC) plays a crucial role in various metabolic pathways, including gluconeogene...
<div><p>Differentiation signaling results in reprogramming of cellular gene expression that leads to...
International audienceThe nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) ...
<p>Real-time qPCR analysis of <i>LacZ</i> (<b>A</b>), PPARγ (<b>B</b>), and adiponectin (<b>C</b>) e...
AbstractAdipocyte differentiation is controlled by a tightly regulated transcriptional cascade in wh...
Abstract Background Adipose tissues serve not only as a store for energy in the form of lipid, but a...
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate expression o...
Peroxisome-proliferator-activated receptor γ (PPARγ) regulates glucose and lipid homeostasis, insuli...
<div><p>Adipose tissue renewal and obesity-driven expansion of fat cell number are dependent on prol...
Adipose tissue renewal and obesity-driven expansion of fat cell number are dependent on proliferatio...
The nuclear receptor PPARγ is a key regulator of adipogenesis, and alterations of its function are a...
International audienceThe nuclear receptor peroxisome proliferator-activated receptor (PPAR) is a tr...
The nuclear receptor PPAR γ is a key regulator of adipogenesis, and alterations of its function are ...
The nuclear receptor PPAR γ is a key regulator of adipogenesis, and alterations of its function are ...
AbstractPeroxisome proliferator-activated receptor (PPAR) γ was shown to be required for adipocyte f...
Pyruvate carboxylase (PC) plays a crucial role in various metabolic pathways, including gluconeogene...
<div><p>Differentiation signaling results in reprogramming of cellular gene expression that leads to...
International audienceThe nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) ...
<p>Real-time qPCR analysis of <i>LacZ</i> (<b>A</b>), PPARγ (<b>B</b>), and adiponectin (<b>C</b>) e...
AbstractAdipocyte differentiation is controlled by a tightly regulated transcriptional cascade in wh...
Abstract Background Adipose tissues serve not only as a store for energy in the form of lipid, but a...