<p>(<b>A</b>) Tet induced HEK293 T-REx™ Nox4 cells were treated for 1h with 100 µM CORM (a CO donor) or RuCl (the control molecule). Histogram shows the RLU sum obtained from the 45 min kinetic of Nox4 activity from 5×10<sup>5</sup> cells assessed by chemiluminescence. * p<0.05 versus RuCl treated cells. (<b>B</b>) 5×10<sup>5</sup> C-20/A4 chondrocytes were pre-treated for 1 h with 100 µM CORM or RuCl. Nox4 activity was then assessed by chemiluminescence. Results are expressed as percentage of RuCl treated cells. Values represent the mean +/− S.D. of determinations in triplicate obtained the same day. * p<0.05 versus RuCl treated cells. (<b>C</b>) C-20/A4 Nox4A chondrocytes were stimulated with 2 ng/ml IL-1β and treated with 100 µM CORM or ...
International audienceSmall amounts of carbon monoxide (CO) are continuously produced in mammals. Th...
Interleukin-1β (IL-1β) activates the production of reactive oxygen species (ROS) and secretion of MM...
Carbon monoxide (CO) is produced endogenously by heme oxygenase (HO) enzymes. HO-1 is highly express...
<p>(<b>A</b>) Predicted linear domain structure of Nox4A, the functional isoform and Nox4B, deleted ...
<p>(<b>A</b>) C-20/A4 chondrocytes were treated or not with 10 or 25 µM CoPP-IX for 48 h. Nox4 activ...
We have investigated the effects of a carbon monoxide-releas-ing molecule, tricarbonyldichlororuthen...
During radiotherapy procedures, radiation-induced bystander effect (RIBE) can potentially lead to ge...
<p>Assessment of proliferation in hVMbclX<sub>L</sub> cells receiving 25 parts per million (ppm) CO ...
Reactive Oxygen Species (ROS) are regulators of redox-sensitive cell-signaling pathways. In osteoart...
<p>(<b>A</b> and <b>B</b>) C-20/A4 chondrocytes overexpressing Nox4A or Nox4B were induced or not fo...
Background: Low concentrations of carbon monoxide (CO) have anti-inflammatory effects and can reduce...
Objective: To investigate the effects and potential mechanisms of preconditioning of tricarbonyldich...
The novel positive-contrast magnetic resonance imaging (MRI) marker C4 consists of an aqueous soluti...
<p>(A) MMP activity, (B) MMP-1 protein, (C) MMP-3 protein levels in the culture medium. Cells were s...
International audienceReactive oxygen species (ROS) are regulators of redox-sensitive cell signaling...
International audienceSmall amounts of carbon monoxide (CO) are continuously produced in mammals. Th...
Interleukin-1β (IL-1β) activates the production of reactive oxygen species (ROS) and secretion of MM...
Carbon monoxide (CO) is produced endogenously by heme oxygenase (HO) enzymes. HO-1 is highly express...
<p>(<b>A</b>) Predicted linear domain structure of Nox4A, the functional isoform and Nox4B, deleted ...
<p>(<b>A</b>) C-20/A4 chondrocytes were treated or not with 10 or 25 µM CoPP-IX for 48 h. Nox4 activ...
We have investigated the effects of a carbon monoxide-releas-ing molecule, tricarbonyldichlororuthen...
During radiotherapy procedures, radiation-induced bystander effect (RIBE) can potentially lead to ge...
<p>Assessment of proliferation in hVMbclX<sub>L</sub> cells receiving 25 parts per million (ppm) CO ...
Reactive Oxygen Species (ROS) are regulators of redox-sensitive cell-signaling pathways. In osteoart...
<p>(<b>A</b> and <b>B</b>) C-20/A4 chondrocytes overexpressing Nox4A or Nox4B were induced or not fo...
Background: Low concentrations of carbon monoxide (CO) have anti-inflammatory effects and can reduce...
Objective: To investigate the effects and potential mechanisms of preconditioning of tricarbonyldich...
The novel positive-contrast magnetic resonance imaging (MRI) marker C4 consists of an aqueous soluti...
<p>(A) MMP activity, (B) MMP-1 protein, (C) MMP-3 protein levels in the culture medium. Cells were s...
International audienceReactive oxygen species (ROS) are regulators of redox-sensitive cell signaling...
International audienceSmall amounts of carbon monoxide (CO) are continuously produced in mammals. Th...
Interleukin-1β (IL-1β) activates the production of reactive oxygen species (ROS) and secretion of MM...
Carbon monoxide (CO) is produced endogenously by heme oxygenase (HO) enzymes. HO-1 is highly express...