HFD induces pro-inflammatory markers and affects time-dependently c/EBPα, hepcidin, and FPN-1 expression.
- Rosaria Meli (424924)
- Giuseppina Mattace Raso (424925)
- Carlo Irace (387397)
- Raffaele Simeoli (424926)
- Antonio Di Pascale (387398)
- Orlando Paciello (296217)
- Teresa Bruna Pagano (424927)
- Antonio Calignano (424928)
- Alfredo Colonna (387399)
- Rita Santamaria (387400)
Publication date
June 2013
DOIAbstract
<p>(A) Real time-PCR of IL-6, (B) c/EBPα and (C) hepcidin mRNA in liver extracts from CD and HFD fed rats for 5 or 8 weeks. (D) Immunoblot of ferroportin (FPN-1) is shown. The bands were densitometrically quantified and plotted. (E) Real time-PCR of hepatic leptin mRNA and (F) serum leptin level, expressed as pg/ml, are shown. *P<0.05; **P<0.01, and ***P<0.001 vs CD; ##P<0.01 vs HFD 5 weeks.</p
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