mRNA expression of the GDNF system in the muscularis propria of the human colon.
- Martina Böttner (425141)
- Martina Barrenschee (359697)
- Ines Hellwig (425142)
- Jonas Harde (425143)
- Jan-Hendrik Egberts (425144)
- Thomas Becker (345029)
- Dimitri Zorenkov (425145)
- Karl-Herbert Schäfer (425146)
- Thilo Wedel (374098)
Publication date
June 2013
DOIAbstract
<p>mRNA expression of GDNF (A) and its receptors GFRα1 (B) and RET (C) is significantly down-regulated in patients with DD compared to controls. mRNA levels are determined by qPCR, expression of target genes is normalized to mRNA expression of the house-keeping gene HPRT. Data are shown as mean +/− SEM, n = 20 (controls) and n = 21 (DD), *p<0.05 vs. control.</p
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