<p>At 7 days p.t. with adenovirus knockdown vectors expressing RNAi for <i>lacZ</i> or <i>Ildr2</i> (left) or with adenovirus vectors over-expressing <i>GFP</i> or <i>Ildr2</i> (right), the 10-week-old chow-fed male B6 mice that were used in the 10 day experiments were injected intraperitoneally after 12 hr fast with 2g/kg glucose. The mice used in this experiment are the same mice that on which indirect calorimetry was conducted on day 5 p.t. (A) WT ADKD; (B) OB ADKD; (C) WT ADOX; (D) OB ADOX. In both ADKD and ADOX animals, IPGTT was unaffected.</p
<p>Compounds (black triangles: 30 mg/kg, black circles: 100 mg/kg, grey circles: exendin-4, 1 μg/kg)...
<p>After 16 h fasting, CD1 mice were i.p. injected with GLP-1/<i>h</i>IgG2 (1 µg/mouse). 30 min afte...
<p>Food intake (<i>A</i>), body weight (<i>B</i>) and basal blood glucose (<i>C</i>) were monitored ...
<p>10-week-old B6 male mice were chow-fed, intravenously injected with ADKD and ADOX vectors and sac...
<p>Mice were chow-fed, 10-week-old B6 (WT) or B6.V-Lep<sup>ob/J</sup> (OB) males, at 4 to 5 days p.t...
<p>Mice were chow-fed, 10-week-old B6 (WT) males, intravenously injected with ADKD vectors expressin...
<p>Mice were chow-fed, 10-week-old B6.V-Lep<sup>ob/J</sup> (OB) males, intravenously injected with A...
<p>A and B, Three-month old male mice (5 for each genotype) were fasted for six h, and intraperitone...
<p>Mice were chow-fed, 10-week-old B6 (WT) males, intravenously injected with ADOX vectors expressin...
<p>To identify short-term effects of changes in <i>Ildr2</i> expression, hepatocytes from five 10-we...
<p>A, Western blot analysis of FLAG-tagged ANGPTL2 in the liver (upper panel: lean mice, lower panel...
<p>(A) Blood glucose levels in control Ad-shCon- or Ad-shKLF11-injected db/m mice 7 days after injec...
<p>(A) Mice fed the SC diet (solid lines), LC diet (dashed lines) and SR diet (dotted lines) were fa...
<p>Male ob/ob mice approximately 9 weeks of age were administered PF-05231023 IV (a) or SC (c) and O...
<p>Mice were chow-fed, 10-week-old B6.V-Lep<sup>ob/J</sup> (OB) males, intravenously injected with A...
<p>Compounds (black triangles: 30 mg/kg, black circles: 100 mg/kg, grey circles: exendin-4, 1 μg/kg)...
<p>After 16 h fasting, CD1 mice were i.p. injected with GLP-1/<i>h</i>IgG2 (1 µg/mouse). 30 min afte...
<p>Food intake (<i>A</i>), body weight (<i>B</i>) and basal blood glucose (<i>C</i>) were monitored ...
<p>10-week-old B6 male mice were chow-fed, intravenously injected with ADKD and ADOX vectors and sac...
<p>Mice were chow-fed, 10-week-old B6 (WT) or B6.V-Lep<sup>ob/J</sup> (OB) males, at 4 to 5 days p.t...
<p>Mice were chow-fed, 10-week-old B6 (WT) males, intravenously injected with ADKD vectors expressin...
<p>Mice were chow-fed, 10-week-old B6.V-Lep<sup>ob/J</sup> (OB) males, intravenously injected with A...
<p>A and B, Three-month old male mice (5 for each genotype) were fasted for six h, and intraperitone...
<p>Mice were chow-fed, 10-week-old B6 (WT) males, intravenously injected with ADOX vectors expressin...
<p>To identify short-term effects of changes in <i>Ildr2</i> expression, hepatocytes from five 10-we...
<p>A, Western blot analysis of FLAG-tagged ANGPTL2 in the liver (upper panel: lean mice, lower panel...
<p>(A) Blood glucose levels in control Ad-shCon- or Ad-shKLF11-injected db/m mice 7 days after injec...
<p>(A) Mice fed the SC diet (solid lines), LC diet (dashed lines) and SR diet (dotted lines) were fa...
<p>Male ob/ob mice approximately 9 weeks of age were administered PF-05231023 IV (a) or SC (c) and O...
<p>Mice were chow-fed, 10-week-old B6.V-Lep<sup>ob/J</sup> (OB) males, intravenously injected with A...
<p>Compounds (black triangles: 30 mg/kg, black circles: 100 mg/kg, grey circles: exendin-4, 1 μg/kg)...
<p>After 16 h fasting, CD1 mice were i.p. injected with GLP-1/<i>h</i>IgG2 (1 µg/mouse). 30 min afte...
<p>Food intake (<i>A</i>), body weight (<i>B</i>) and basal blood glucose (<i>C</i>) were monitored ...