IL-11 supplementation studies in a fetal lung explant culture system.

<p>(A) Representative examples of fetal lung explants treated daily with increasing concentrations of recombinant IL-11, after 4 days in culture. Original magnification: ×25. (B) Number of peripheral airway buds ; (C) Epithelial perimeter; (D) Area; (E) External perimeter of lung explants treated with IL-11. Results are expressed as ratio of day 4 (D₄) and day 0 (D₀) of culture (D₄/D₀ ratio), and also as absolute number in D₀ (black bar) and D₄ (white bar). p<0.05: ^*<i>vs.</i> IL-11 at 0 pg/mL (control), ^§<i>vs.</i> IL-11 at 0.1 pg/mL, ^¥<i>vs</i>. IL-11 at 1 pg/mL.