<p>A. Flow cytometry results showing surface antibody expression four days after treatment to switch to IgG1. B. Analysis of flow cytometry data related to formation of IgG1 in ALKBH1 deficient splenic B cells normalized to the switching rate of Alkbh1<sup>+/+</sup> B cells. Four mice were used for each genotype and error bars represent standard deviations from these four independent experiments.</p
Antibody class switching is induced by B-cell activators in the presence of cytokines. The identity ...
Mouse splenic marginal zone (MZ) B cells and B1 B cells enriched in the peritoneal cavity respond pr...
Eomesf/fCd23cre/+ and littermate controls were immunized with NP-KLH precipitated in alum. Splenic B...
Inbred mouse strains used for gene manipulation studies vary in many respects, including immune syst...
<p>(A) Splenic B cell proliferation as assayed by dilution of CFSE assayed ∼44 hrs after treatment t...
<p>(<b>A</b>) FACS profiles of IgG<sub>1</sub> vs IgG<sub>3</sub> expression by B220<sup>+</sup>IgM<...
<p>(A) Splenic B cells from C57BL/6 mice were cultured for 4 days with IL-4, then for 4 days with IL...
Mouse splenic marginal zone (MZ) B cells and B1 B cells enriched in the peritoneal cavity respond pr...
<p>(A) Graph of mean number ± SD of splenic B cells (CD19<sup>+</sup>) determined by flow cytometry ...
<p>A. Flow cytometric analysis to enumerate GC B cells at various sites in control and <i>Gnai2 </i>...
<p>B6 WT (filled squares, solid lines) and CD73KO (empty circles, dashed lines) mice were immunized ...
<p>WT (gray bars) and <i>Rad1</i><sup>K185R</sup> (black bars) B cells were tested for their ability...
The murine B cell lymphoma CH12.LX, which bears cell surface IgM specific for the phosphatidyl choli...
<p>Splenic B cells from WT and Mlh1<sup>+/−</sup> (<b>A</b>) or WT and Msh2<sup>+/−</sup> (<b>B</b>)...
Antibody-mediated immunity is highly protective against disease. The majority of current vaccines co...
Antibody class switching is induced by B-cell activators in the presence of cytokines. The identity ...
Mouse splenic marginal zone (MZ) B cells and B1 B cells enriched in the peritoneal cavity respond pr...
Eomesf/fCd23cre/+ and littermate controls were immunized with NP-KLH precipitated in alum. Splenic B...
Inbred mouse strains used for gene manipulation studies vary in many respects, including immune syst...
<p>(A) Splenic B cell proliferation as assayed by dilution of CFSE assayed ∼44 hrs after treatment t...
<p>(<b>A</b>) FACS profiles of IgG<sub>1</sub> vs IgG<sub>3</sub> expression by B220<sup>+</sup>IgM<...
<p>(A) Splenic B cells from C57BL/6 mice were cultured for 4 days with IL-4, then for 4 days with IL...
Mouse splenic marginal zone (MZ) B cells and B1 B cells enriched in the peritoneal cavity respond pr...
<p>(A) Graph of mean number ± SD of splenic B cells (CD19<sup>+</sup>) determined by flow cytometry ...
<p>A. Flow cytometric analysis to enumerate GC B cells at various sites in control and <i>Gnai2 </i>...
<p>B6 WT (filled squares, solid lines) and CD73KO (empty circles, dashed lines) mice were immunized ...
<p>WT (gray bars) and <i>Rad1</i><sup>K185R</sup> (black bars) B cells were tested for their ability...
The murine B cell lymphoma CH12.LX, which bears cell surface IgM specific for the phosphatidyl choli...
<p>Splenic B cells from WT and Mlh1<sup>+/−</sup> (<b>A</b>) or WT and Msh2<sup>+/−</sup> (<b>B</b>)...
Antibody-mediated immunity is highly protective against disease. The majority of current vaccines co...
Antibody class switching is induced by B-cell activators in the presence of cytokines. The identity ...
Mouse splenic marginal zone (MZ) B cells and B1 B cells enriched in the peritoneal cavity respond pr...
Eomesf/fCd23cre/+ and littermate controls were immunized with NP-KLH precipitated in alum. Splenic B...