<p>The names of the three SNPs are shown on top, and the chromosomal positions on chromosome 6 are marked in the ruler in the middle. The <i>HLA-DPA1</i> and <i>HLA-DPB1</i> genes are shown as arrows in the bottom, with the exons shown as black boxes, introns as white boxes, and un-translated regions as gray boxes/arrows.</p
<p>Sequenced sub-regions are marked by colored blocks (top). Distances (kb) are to scale from the hu...
<p>(A) Noncoding regions, including the promoter, intron, and intergenic sequence are represented by...
(black line). Data from immune related genes and control genes are included. Abscise represents posi...
<p>The blue rectangles span the regions from the start to the stop points of the Class II genes: <i>...
<p>Gene are indicated as black rectangles with grey 3'UTR. Bold red and blue SNPs represent miSNPs a...
<p>HLA-E, -H, -G, -F and HFE relative location and distance from HLA-A on chromosome 6.</p
<p>Association results across the major histocompatibility complex (MHC) on chromosome 6, conditione...
<p>A: HPSE gene structure. Filled boxes represent the 13 exons (5′→3′). Arrows show the locations of...
Association results across the major histocompatibility complex (MHC) on chromosome 6, conditioned o...
<p>Two probes in the HLA region on chromosme 6 showing significant association with PD risk SNPs are...
<p>The positions for each SNP are listed on the x-axis, and are based on the genome assembly hg19. S...
<p>Association results across the major histocompatibility complex (MHC) on chromosome 6, conditione...
<p>A 3,145 kb segment of the extended HLA gene region is shown. The LTA, TNF, and LST1 loci encoded ...
HLA class-II proteins are cell-surface molecules that present antigens to T cells, and their express...
<p>Panels on the left are regional association plots for all variants in the MHC region; each diamon...
<p>Sequenced sub-regions are marked by colored blocks (top). Distances (kb) are to scale from the hu...
<p>(A) Noncoding regions, including the promoter, intron, and intergenic sequence are represented by...
(black line). Data from immune related genes and control genes are included. Abscise represents posi...
<p>The blue rectangles span the regions from the start to the stop points of the Class II genes: <i>...
<p>Gene are indicated as black rectangles with grey 3'UTR. Bold red and blue SNPs represent miSNPs a...
<p>HLA-E, -H, -G, -F and HFE relative location and distance from HLA-A on chromosome 6.</p
<p>Association results across the major histocompatibility complex (MHC) on chromosome 6, conditione...
<p>A: HPSE gene structure. Filled boxes represent the 13 exons (5′→3′). Arrows show the locations of...
Association results across the major histocompatibility complex (MHC) on chromosome 6, conditioned o...
<p>Two probes in the HLA region on chromosme 6 showing significant association with PD risk SNPs are...
<p>The positions for each SNP are listed on the x-axis, and are based on the genome assembly hg19. S...
<p>Association results across the major histocompatibility complex (MHC) on chromosome 6, conditione...
<p>A 3,145 kb segment of the extended HLA gene region is shown. The LTA, TNF, and LST1 loci encoded ...
HLA class-II proteins are cell-surface molecules that present antigens to T cells, and their express...
<p>Panels on the left are regional association plots for all variants in the MHC region; each diamon...
<p>Sequenced sub-regions are marked by colored blocks (top). Distances (kb) are to scale from the hu...
<p>(A) Noncoding regions, including the promoter, intron, and intergenic sequence are represented by...
(black line). Data from immune related genes and control genes are included. Abscise represents posi...