ROC of tPSA, %fPSA and PSAD for predicting the result of prostate biopsy for Gleason Score≥7 PCa vs. Gleason Score <7 and non-PCA in different age groups.

<p>(a)All study population: AUC-tPSA vs. AUC-%fPSA (P<0.001), AUC-PSAD vs. AUC-tPSA(P = 0.05), AUC-model vs. AUC-tPSA(P>0.05); (b) Age≤60 yr, AUC-tPSA vs. AUC-%fPSA (P>0.05), AUC-PSAD vs. AUC-tPSA(P>0.05), AUC-model vs. AUC-tPSA(P>0.05); (c) Age 61–80 yr, AUC-tPSA vs. AUC-%fPSA (P<0.001), AUC-PSAD vs. AUC-tPSA(P>0.05), AUC-model vs. AUC-tPSA(P>0.05); (d) Age≥81 yr, AUC-tPSA vs. AUC-%fPSA (P>0.05), AUC-PSAD vs. AUC-tPSA(P>0.05), AUC-model vs. AUC-tPSA(P>0.05).