Mtap effect on tumor formation in <i>Eµ-Myc</i> and <i>Pten</i><sup>+/−</sup> mice.
- Yuwaraj Kadariya (426943)
- Baiqing Tang (426944)
- Liqun Wang (426945)
- Tahseen Al-Saleem (215765)
- Kyoko Hayakawa (426946)
- Michael J. Slifker (426947)
- Warren D. Kruger (121481)
Publication date
June 2013
DOIAbstract
<p>A. Tumor-free survival of <i>Eµ-myc Mtap<sup>+/+</sup></i> and <i>Eµ-myc Mtap<sup>lacZ/+</sup></i> mice. Sibling <i>Eµ-myc Mtap<sup>lacZ/+</sup></i> (n = 48) and <i>Eµ-myc Mtap<sup>+/+</sup></i> (n = 42) were monitored daily for tumor formation and/or death for 368 days (p<0.001) B. Tumor-free survival of <i>Mtap<sup>+/+</sup> Pten<sup>+/−</sup></i> and <i>Mtap<sup>lacZ/+</sup> Pten<sup>+/−</sup></i> mice. Sibling of <i>Mtap<sup>+/+</sup> Pten<sup>+/+</sup></i> (n = 32) and <i>Mtap<sup>lacZ/+</sup> Pten<sup>+/−</sup></i> (n = 32) were monitored daily and followed for 450 days (p<0.031). Tick marks show censored observations (deaths with no detectable tumor).</p
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