<p>Illustration of the target gene network from our analysis where differential expression may result from activation or inhibition of 3 transcription regulators, CLOCK, SCREB and XBP1, each with activation status predicted to be altered by parasite infection and reversed by BW720c in our analysis (see text). Red means up-regulated in TBL20 compared to BL20 (range 1.7–117 fold); green is down-regulated in TBL20 (range 1.7–110 fold); grey, no differential expression.</p
<p>Temporal expression patterns of 7,991 genes modulated in concordance with key steps of viral repl...
<p>A. Schematics depicting the promoter region of the mouse <i>Fbxl21</i> gene, E' indicate non-cano...
<p>Overall summary with the names of the associated functional interaction networks identified as si...
<p>Top ranking genes with (A) elevated (+) or (B) repressed (−) expression in parasite infected TBL2...
<p>The predictions of activation or inhibition of transcription regulators are based on the directio...
<p>Transcription regulators identified in the Ingenuity Pathway Analysis Database (IPA) that were di...
<p>Profiles were derived from pairwise comparisons, BL20 vs TBL20; TBL20 vs TBL20_BW720c_24 h; TBL20...
<p>A comparative analysis for enrichment in cellular molecular functions was carried out for each da...
<p>Summary of all significantly (p<0.05) up- and down-regulated parasite genes with a respective ave...
<p>A-C. Enrichment for the DNA binding motif of CLOCK:BMAL1 (A), tissue-specific transcription facto...
<p>Systematic RNAi-mediated downregulation of network neighborhood genes in dexamethasone-synchroniz...
One component of the circadian clock in mammals is the Clock-Bmal1 heterodimeric transcription facto...
<p>(<b>A</b>) Illustration of expression patterns of differentially expressed genes (THP1r2<i>Mtb</i...
Expression levels are indicated by a color scale and represent normalized differences between infect...
<p>The left figure shows the numbers of genes that were up-regulated and down-regulated at 24AP and ...
<p>Temporal expression patterns of 7,991 genes modulated in concordance with key steps of viral repl...
<p>A. Schematics depicting the promoter region of the mouse <i>Fbxl21</i> gene, E' indicate non-cano...
<p>Overall summary with the names of the associated functional interaction networks identified as si...
<p>Top ranking genes with (A) elevated (+) or (B) repressed (−) expression in parasite infected TBL2...
<p>The predictions of activation or inhibition of transcription regulators are based on the directio...
<p>Transcription regulators identified in the Ingenuity Pathway Analysis Database (IPA) that were di...
<p>Profiles were derived from pairwise comparisons, BL20 vs TBL20; TBL20 vs TBL20_BW720c_24 h; TBL20...
<p>A comparative analysis for enrichment in cellular molecular functions was carried out for each da...
<p>Summary of all significantly (p<0.05) up- and down-regulated parasite genes with a respective ave...
<p>A-C. Enrichment for the DNA binding motif of CLOCK:BMAL1 (A), tissue-specific transcription facto...
<p>Systematic RNAi-mediated downregulation of network neighborhood genes in dexamethasone-synchroniz...
One component of the circadian clock in mammals is the Clock-Bmal1 heterodimeric transcription facto...
<p>(<b>A</b>) Illustration of expression patterns of differentially expressed genes (THP1r2<i>Mtb</i...
Expression levels are indicated by a color scale and represent normalized differences between infect...
<p>The left figure shows the numbers of genes that were up-regulated and down-regulated at 24AP and ...
<p>Temporal expression patterns of 7,991 genes modulated in concordance with key steps of viral repl...
<p>A. Schematics depicting the promoter region of the mouse <i>Fbxl21</i> gene, E' indicate non-cano...
<p>Overall summary with the names of the associated functional interaction networks identified as si...