Hx deficiency results in increased iron deposits in the duodenum.

<p>(A) Total iron content in the duodenum of 2 month-old wild-type and Hx-null mice measured by ICP-MS. Values are expressed as μg iron/g wet tissue. Data represent mean ± SEM; n=10; * = P<0.05. (B) Duodenal sections of a wild-type mouse (i, ii) and an Hx-null mouse (iii, iv) at 2 months of age stained with DAB enhanced Perls’ reaction. Note the more intense staining in the duodenum of the Hx-null mouse. Bar i, iii = 500µm; bar ii, iv = 100µm.